Nearly half of drug candidates fail because of inadequate safety in pre-clinical testing, representing an expensive loss of investment and lost opportunity. Often, drugs are found to cause toxicity through off-target activity. Therefore, understanding how drugs interact with their target receptors, and minimizing off-target activity is crucial to developing effective medications. Over my career, I’ve […]Read More
Author: Richard Cramer
Dr. Richard D. Cramer III is a Senior Vice President at Certara. He invented CoMFA (Comparative Molecular Field Analysis), the first and most widely-used 3D-QSAR technique for molecular discovery. Dr. Cramer, a baseball fanatic, also co-founded, as its CTO, STATS, today the leading worldwide supplier of sports statistical information.