The use of physiologically-based pharmacokinetic (PBPK) modeling for drug development is well-established and is now routinely used by the pharmaceutical industry, regulators, and researchers. In this blog post, I’ll discuss a novel application that combined PBPK and Bayesian modeling to help clinicians optimize dosing at the point of patient care. This application was used to […]Read More
Author: Manoranjenni Chetty
Dr Manoranjenni Chetty is a Project Co-ordinator & Scientific Advisor at Certara. She has extensive experience in Academia, hospital pharmacy, and the pharmaceutical industry. Mano currently holds honorary Professor positions at the University of KwaZulu Natal (South Africa) and the University of Technology Sydney (Australia). She has several publications in her areas of research interest, which include PBPK/PD modeling, inter-individual variability in PK and PD and therapeutic drug monitoring.