The Certara Blog

Author: Krishna Machavaram

Dr. Krishna Machavaram is a Senior Scientist at Certara. He has several years of Pharma/CRO experience in the PK/PD aspects of drug discovery and development. Since joining Simcyp in 2010, he has worked and led multiple Simcyp projects with a major focus on developing tools for modelling complex in vitro data (SIVA toolkit project) and predicting disease-drug interactions mediated via suppression of drug metabolizing enzymes. After qualifying as a Pharmacist, he received his PhD in clinical pharmacokinetics from Kakatiya University, and got his post-doctoral training in the aspects of lymphatic transport and pharmacokinetics of therapeutic proteins from Monash University. His research interests include predicting complex drug-drug interactions, IVIVE, PBPK modeling of biologics and special populations.

Recent Posts

Analyzing Complex In Vitro Experiments: It’s Not as Hard as You Think

Analyzing in vitro experiments can be challenging and time consuming. Yet, crucial decisions depend on accurate data analysis and interpretation early in development. Unfortunately, most lab-based scientists lack access to state-of-the-art models for analyzing in vitro data. A new tool enables the analysis of data generated from complexin vitro studies. These studies include assays using […]

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