The Certara Blog

Author: Iain Gardner

Dr. Gardner has been at Certara since 2011. He leads the science team that is responsible for further developments of the population based physiologically based PK-PD Simulators to meet the needs of our consortium members.

Recent Posts

Predicting mAb Pharmacokinetics in Humans with a Minimal PBPK Model

Monoclonal antibodies (mAbs) and their derivatives are a rapidly growing segment of the pharmaceutical industry’s pipeline. In fact, more than 40 mAbs and derivatives have been approved for a variety of therapeutic applications; around 500 mAbs and derivatives are currently in different stages of development. Monoclonal antibodies have pharmacokinetic (PK) properties that are quite distinct from that […]

Read More

5 Updates to the Simcyp Simulator You’ll Be Psyched About

The Simcyp™ Population-based Simulator streamlines drug development through the modelling and simulation of physiologically-based pharmacokinetics (PK) and pharmacodynamics (PD) in virtual patient populations. It incorporates numerous databases containing human physiological, genetic and epidemiological information. By integrating this information with in vitro or clinical data, the Simulator can predict PK/PD behavior in ‘real-world’ populations. It can be used to select […]

Read More
Learn More LinkedIn Twitter Facebook Email Subscribe to the Blog