Leveraging PBPK Modeling and Simulation for Neonatal and Infant Drug Development

Despite increased regulatory support for pediatric drug development, sponsors still face ethical, economic and practical constraints. Indeed, while children represent about 40% of the world’s population, only 10% of the drugs on the market have been approved for pediatrics. Children are not small adults, and all children are not the same. In particular, children under … Continued

Agile Access to Drug Discovery Data with D360

This webinar focused on using D360 to get the most out of drug discovery data by utilizing simple query-building with integrated chemistry tools and analysis tools, dynamically linked data visualizations, and easy to use annotations.

CODEx Rheumatoid Arthritis Clinical Outcomes Database

The current version of the database includes clinical safety and efficacy information on all biologics as well as newer synthetic DMARDs currently approved or in development for rheumatoid arthritis (RA). Information on older treatment options (MTX and other DMARDs) was included if they are used as active controls.

Quantify Chronic Kidney Disease Clinical Outcomes Database

The current version of the database includes clinical safety and efficacy information on treatment options currently approved or in development for Chronic Kidney Disease (CKD) progression
in patients with Type 2 Diabetes Mellitus (T2DM) and overt albuminuria/proteinuria, as well as patients with IGA nephropathy.

Quantify CD Clinical Outcomes Database

The current version of the database contains information from randomized controlled trails on all current biologic and small molecule drugs that are evaluated for moderate-to-severe Crohn’s disease in patients that failed conventional treatment.

Quantify AS Clinical Outcomes Database

The Quantify AS Clinical Outcomes Database is developed to document clinical safety and efficacy information from randomized controlled trials investigating biologics currently approved or in development for ankylosing spondylitis (AS).

Quantify ALL Clinical Outcomes Database

The Quantify Acute Lymphoblastic Leukemia (ALL) Clinical Outcomes Database documents clinical efficacy information in infants, children, and adults following salvage treatment for relapsed/refractory patients.

Quantify AD Clinical Outcomes Database

The current version of the database includes clinical safety and efficacy information on all symptomatic drugs as well as newer Abeta drugs currently approved or in development for Alzheimer Disease (AD).