About Us

Certara is dedicated to improving human health by offering a broad spectrum of software products and services, with special focus on supporting translational approaches to drug development.

Scientific Informatics

Access, visualize, and analyze drug discovery, pre-clinical and clinical data

D360

Molecular Modeling and Simulation

Predictive science for drug discovery and other life sciences

PBPK Modeling and Simulation

Conduct simulations in virtual patient populations based on in vitro and clinical data.

PK/PD Modeling and Simulation

Analyze, manage, report, and validate preclinical and clinical data.

Trial Design

Minimize risks and guide decision making for drug trials.

Trial Simulator

Discovery Through Phase IV Clinical Trials

Pharsight Consulting Services

Support your strategic drug development decisions and new drug approvals through quantitative analysis and predictive models of diseases, drugs and clinical trials.

Simcyp Consultancy Services

Consultancy and guidance on a broad spectrum of DMPK issues, including optimal design for metabolic drug-drug interaction studies, interpretation of data and prediction of in vivo ADME from in vitro studies.

PBPK Modeling and Simulation

Our Practice

Multi-disciplinary expert scientific team with expertise in pharmacometrics, PK analysis and programming, biostatistics, and medical writing.

Model-Based Insights, Unparalleled Experience

Supporting Drug Approvals

Our team of more than 50 scientists has supported eleven drug approvals in the last two years.

Learn More

Resource Library

Search Certara's Resource Library to find papers, presentations, and webinars of interest

SEARCH RESOURCES

Access to some of our resources requires a registered account and "Log In" is required.

Products

Certara offers predictive science and informatics solutions that enable cross-disciplinary and translational approaches to drug development.

PBPK Modeling and Simulation

Simcyp Animal

Simcyp has developed a whole-body physiologically-based pharmacokinetic (PBPK) modelling platform for rat, dog and knock-out mouse which can be used to:

assess PK properties
evaluate formulation and food effects on drug absorption
predict concentration-time profiles in plasma, tissues and organs
investigate the formation and kinetics of primary metabolites.

Simulations with Simcyp Animal can help in the identification of key data requirements and the design of subsequent experiments and have been used to increase confidence in in vitro – in vivo extrapolation (IVIVE) before moving to human simulations.

When used in conjunction with the Simcyp Population-based Simulator, Simcyp Animal allows comparison of human and animal data without relying upon allometric scaling, which may not be a valid approach for some parameters.

Simcyp is now part of Certara, continues delivering leading-edge science, accelerating drug discovery and development for its Consortium of member pharma companies. More about Simcyp on simcyp.com

Simcyp Population-based Simulator Predict drug absorption and disposition in virtual patient populations, including paediatrics. Learn more at simcyp.com

Consultancy for a broad spectrum of DMPK issues, including optimal design for metabolic drug-drug interaction studies, interpretation of data and prediction of in vivo ADME from in vitro studies Learn more at simcyp.com

Interactive workshops and courses cover the concepts of model-based drug development with focus on incorporating population variability into mechanistic prediction of PK and modelling of PK-PD Explore upcoming events at simcyp.com

Key Publications Simcyp actively publishes the results of its research in the form of conference abstracts and peer-reviewed papers. Explore citations and published articles